4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde
4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde
CAS: 50670-58-1
Molecular Formula: C13H9BrO
4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde - Names and Identifiers
| Name | 4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde |
| Synonyms | 4-(4-Bromophenyl)benzaldehyde 4'-Bromo-[1,1'-biphenyl]-4-carbaldehyde 4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde [1,1'-Biphenyl]-4-carboxaldehyde, 4'-bromo- 4'-Bromo-4-formylbiphenyl, 4-(4-Bromophenyl)benzaldehyde |
| CAS | 50670-58-1 |
4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde - Physico-chemical Properties
| Molecular Formula | C13H9BrO |
| Molar Mass | 261.13 |
| Density | 1.430 |
| Melting Point | 135-140 °C |
| Boling Point | 374.1±25.0 °C(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD05980925 |
4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde - Upstream Downstream Industry
| Downstream Products | METHYL 4'-BROMO[1,1'-BIPHENYL]-4-CARBOXYLATE |
4'-Bromo-[1,1'-biphenyl]-4-carboxaldehyde - Introduction
4 '-Bromo-[1,1'-biphenyl]-4-carbohyde (4 '-Bromo-[1,1'-biphenyl]-4-carbohyde) is an organic compound with the chemical formula C13H9BrO. The following is a brief description of its nature, use, preparation and safety information:
Nature:
-Appearance: light yellow to orange yellow crystalline powder
-Melting point: about 80-85 ℃
-Boiling point: about 335 ℃
-Solubility: Soluble in organic solvents such as ethanol, dichloromethane and dimethyl sulfoxide
Use:
-As an organic synthesis intermediate, it can be used to synthesize biologically active compounds
-It has certain applications in the field of medicine, such as the synthesis of anti-cancer drugs and other biologically active substances
Preparation Method:
4 '-Bromo-[1,1'-biphenyl]-4-carboxaldehyde can be synthesized by the following steps:
1. 4-bromobenzaldehyde and diphenyl sodium carbonate are reacted under the protection of nitrogen under the catalysis of cuprous iodide (CuI) to generate 1,1 '-biphenyl.
2. Oxidation of 1,1 '-biphenyl with iodine ethanol solution generates 4'-Bromo-[1,1 '-biphenyl]-4-carboxaldehyde.
Safety Information:
- 4 '-Bromo-[1,1'-biphenyl]-4-carboxalaldehyde should be careful to avoid contact with skin, eyes and mucous membranes during use and storage.
-Pay attention to the use of adequate ventilation equipment during operation and avoid dust generation.
-In case of inhalation or contact, promptly move away from the scene and seek medical assistance.
-Please store properly, avoid contact with flammable substances, and place away from fire and heat sources.
Nature:
-Appearance: light yellow to orange yellow crystalline powder
-Melting point: about 80-85 ℃
-Boiling point: about 335 ℃
-Solubility: Soluble in organic solvents such as ethanol, dichloromethane and dimethyl sulfoxide
Use:
-As an organic synthesis intermediate, it can be used to synthesize biologically active compounds
-It has certain applications in the field of medicine, such as the synthesis of anti-cancer drugs and other biologically active substances
Preparation Method:
4 '-Bromo-[1,1'-biphenyl]-4-carboxaldehyde can be synthesized by the following steps:
1. 4-bromobenzaldehyde and diphenyl sodium carbonate are reacted under the protection of nitrogen under the catalysis of cuprous iodide (CuI) to generate 1,1 '-biphenyl.
2. Oxidation of 1,1 '-biphenyl with iodine ethanol solution generates 4'-Bromo-[1,1 '-biphenyl]-4-carboxaldehyde.
Safety Information:
- 4 '-Bromo-[1,1'-biphenyl]-4-carboxalaldehyde should be careful to avoid contact with skin, eyes and mucous membranes during use and storage.
-Pay attention to the use of adequate ventilation equipment during operation and avoid dust generation.
-In case of inhalation or contact, promptly move away from the scene and seek medical assistance.
-Please store properly, avoid contact with flammable substances, and place away from fire and heat sources.
Last Update：2024-04-09 15:18:02
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